Since 1991 his main field of interest was gynecological endoscopy (laparoscopy and hysteroscopy) and he performed more than 7000 operations, introducing at the Policlinico S. Orsola new techniques of minimally invasive surgery in the field of endometriosis and oncology. Originally he was involved in assisted reproduction, through several internships at major European centers and he was involved in the organization of the Center for Assisted Reproduction of the Policlinico S. Orsola in Bologna, Italy.

 He is Director of U.O. Gynecology and Reproductive Pathophysiology of the Policlinico S. Orsola-Malpighi of Bologna from November the 1st 2014.

He is author of over 400 publications, including 320 scientific papers published in peer-reviewed journals surveyed by MEDLINE. Since 1997 he taught “Endoscopic surgical techniques” and “Laparoscopic surgical therapy” at the postgraduate school of Gynecology and Obstetrics of Bologna. Since 2000 Prof. R. Seracchioli organized many workshops about gynecological laparoscopy and hysteroscopic surgical techniques at the Policlinico S. Orsola.   From 2001 to 2007 he joined the Executive Council SEGI as Head of the External Relations Commission. In 2008 he won the Charles Romanini Award with the article entitled “Long-Term Postoperative Oral Contraceptive Therapy and Ovarian Endometrioma Recurrence. A Randomized Controlled Trial” presented to Congress AAGL Las Vegas. He is a Faculty member of ESHRE – European Society of Human Reproduction and Embryology.